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1 × 8.78€
SAM-e, 400mg Double-Strength – 30 tablets
44.59€
Helps support mood and neural function*
Helps support joint comfort and mobility*
Helps support liver health and detoxification*
Quantity discount
| Quantity | 2 | 3 | 4 | 5+ |
|---|---|---|---|---|
| Price | 42.81€ | 41.91€ | 40.58€ | 39.24€ |
Out of stock
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SAM-e
What is Doctor’s Best Doctor’s Best SAM-e?
Doctor’s Best SAM-e is proven to enhance mood and promote cognitive health. It is essential for the healthy metabolism of the major brain transmitters’ dopamine, serotonin and norepinephrine. In addition, SAM-e promotes joint comfort and mobility and supports liver health and detoxification. SAM-e effectiveness has been published in 18 controlled human trials published over 40 years. Doctor’s Best SAM-e uses pharmaceutical grade materials. SAM-e is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. SAM-e optimized for potency, stability, and to survive the stomach acid and reach the intestine (where it is absorbed). Effectiveness of SAM-e has been backed by at least 18 controlled human trials published over almost four decades.
How does it work?
S-Adenosyl Methionine (SAM-e) is produced by the body from ATP and the amino acid methionine which is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAM-e is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAM-e is also required for the biosynthesis of critical neurotransmitters and hormones.
Why should I take Doctor’s Best SAM-e?
SAM-e is a biological compound found in every living cell of the human body, vital to their function, stability and activity and involved in more than one hundred biochemical reactions and specific processes. SAM-e helps promote healthy mood. So if your body is not producing enough SAM-e, you might feel blue or have trouble sleeping. And according to the Center for Disease Control, an estimated 1 in 10 American adults say they are depressed. Supplementing with Doctor’s Best SAM-e can help and improve your quality of life.
23 reviews for SAM-e, 400mg Double-Strength – 30 tablets
Only logged in customers who have purchased this product may leave a review.
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Ecosupplements customer (verified owner) –
take SAMe because I have foie gras. Just a mild form of fatty liver disease. I take it with silibinin/sylibin. 400 mg in the morning on an empty stomach and 400 mg in the evening before going to bed. After two months, SAMe and silibinin were able to lower my transaminases. Gamma-GT as well as GPT and GOT were then back in the normal range. I also gave SAMe to my dog. He had been on corticosteroids for some time for a joint problem. GPT, GOT, gamma-GT and alkaline phosphatase were increased. After three weeks of 2 x 400 mg of SAMe, liver values had returned to normal.
Ecosupplements customer (verified owner) –
This product is amazing. I suffered for years from chronic fatigue, brain fog, poor memory, sleep problems, muscle pain, joint pain, and low mood. SAM-e started changing that for me within days. I sleep better and I have regained energy. The arthritis I was starting to develop doesn’t bother me anymore and I’m focused and efficient at work. I also feel happy and motivated. I don’t know what I would do without it. Dr’s Best is just as effective as the more expensive brands I’ve tried and the price is great. Ecosupplements offers free and fast delivery. I have recommended this product to a dozen friends who have all reported similar results and are absolutely convinced of it. A life changer!
Ecosupplements customer (verified owner) –
don’t know what they put in this thing, but it works. I’m a person who can be easily irritated at times and this stuff keeps me cool, calm and collected. It makes me feel emotionally balanced. I don’t know why I didn’t discover this stuff sooner.
MammaGeek (verified owner) –
I’ve been buying Doctor’s Best SAMe from Ecosupplements for years. This is a great product and Ecosupplements has the best price around.
handyman86326 (verified owner) –
This product is excellent and the price point is about half of that at the local drug store. Automatic shipping ensures that the product arrives timely.
Ecosupplements customer (verified owner) –
High dosage of quality saM-e from a reputable brand. The tablets are enteric coated (important for SAMe absorption and each tablet is individually sealed for freshness (great packaging). I use this as a double claw remedy to support the liver and joints and works great for me. A (noticeable) better mood is a nice bonus too.
Ecosupplements customer (verified owner) –
I bought this for my brother’s depression. He was skeptical at first, but after 3 days he said he noticed a huge boost in energy and mood. I can’t take this brand unfortunately because the arginine base gives me cold sores, so I’m taking the Ecosupplementss Life Extension brand instead. I highly recommend this brand as it seems to be very powerful/effective for depression.
Ecosupplements customer (verified owner) –
Doctors Best has become our favorite family brand! The product is a supplement for improving health, immunity, quality of life, well-being and mood. I bought it out of curiosity after reading “Vitamin” in the title of the search results. It has fulfilled some essential needs that I had until now: a boost of energy and an elimination of fatigue due to long flights and stress.
Ecosupplements customer (verified owner) –
SAM0e is a basic supplement for cystic fibrosis. This brand uses quality ingredients and the tablets are an easy to swallow size. It may have beneficial effects on mood, attention and depression and supports liver function. It is tasteless and tests show it is well absorbed. The package contains a foil wrapper for the tablets.
NEMI (verified owner) –
The price is good ! The shipment to Germany working professionally at a fair cost . Until next time!!
Ecosupplements Customer (verified owner) –
Dear,
Last Friday when my mood is really down, I took one pill and my mood get stable and went to work at the office.
Jaye1104 (verified owner) –
Every morning upon waking up, I take my SAMe 400. It helps me get through my day in such a good way.
It improves my joints considerably. As well as improving my intellectual performance. Protects my liver from the medications that can do harm to your liver.
It enhances my mood and I cannot express enough how much SAMe has helped me live my life comfortably.
I LOVE IT!
Ecosupplements customer (verified owner) –
actually ordered it as a mild antidepressant, although it’s a liver medicine, I’ve heard it helps a lot in improving mood. The size of the pills is huge. I haven’t taken it long enough to talk about effects but I’ll update it once I notice anything.
Ecosupplements Customer (verified owner) –
I Have been taking this product for 4-5 years
No longer have arthritis stiffness or joint pain. Tried other brands that did not produce the same relief. doctors best high potency and dosage works the BEST!
Ecosupplements customer (verified owner) –
Doctor’s Best manufactures SAM-e tablets that deliver the expected efficacy. Not all SAM-e are the same! Based on previous experience, I now avoid those containing ”methionine” only, as SAM-e is effective for anxiety with ”L-methionine”. My daughter went from 3-4 panic attacks a day to 3-4 a day. week on Celexa (an SSRI) to ZERO panic attacks with SAM-e, and her baseline anxiety also decreased, making her more able to enjoy life. Doctor’s Best SAM-e took care of the hives I had because it’s an antihistamine. Good product!
Kitamon (verified owner) –
Great product. My preferred source of SAME. Works with my other joint supplements well & boosts mood too.
Ecosupplements Customer (verified owner) –
Very helpful.
Ecosupplements Customer (verified owner) –
Excellent for health all of us need it
Ecosupplements customer (verified owner) –
trust Dr’s Best as a brand and am glad Ecosupplements stock them. I take SAMe to help me maintain a good mood and for my joints. I take other supplements, especially collagen powder and NOW UCII Undenatured Callgen type 2, which also help my joints. What I notice most about SAMe is that it relieves what can be a bad mood, especially in difficult and stressful times, and I feel good and able to handle difficult situations better. I take 400mg a day to get the result I want. It’s an ongoing expense – but worth it to me.
Lovebeinghealthy (verified owner) –
I have been taking Doctor’s Best SAM-e for a number of years. I appreciate the Ecosupplements discount!
Shelley99 (verified owner) –
I didn’t realize when I ordered this that the pills are in blister packs. We take multiple supplements & every 2 weeks we put them all into one plastic daily dispenser for each of us. This method is also great for travelling. Having these in blister packs is a pain in the butt & a waste for us. The product itself is great.
LB53 (verified owner) –
I find this helps especially during the winter months for me. Very effective product and worth the money!
Ecosupplements Customer (verified owner) –
I really like this product its not always available but I find it really helpful