Doctor’s Best – Benfotiamine with BenfoPure
What is Doctor’s Best Benfotiamine?
Benfotiamine (S-benzoylthiamine-O-monophosphate) is a synthetic derivative of thiamin (Vitamin B1) belonging to the family of compounds known as allithiamines. Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin. Benfotiamine helps maintain healthy cells in the presence of blood glucose, provides support against oxidative stress, and supports healthy aging.
How does it work?
Benfotiamine raises the blood level of thiamin pyrophosphate (TPP), the biologically active coenzyme of thiamin, and stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways. Benfotiamine can greatly improve thiamin status, especially in comparison with regular forms of thiamin. In a randomized, double-blind crossover trial comparing bioavailability of benfotiamine to that of thiamin mononitrate (the most common supplemental form of vitamin B1) in 12 individuals, benfotiamine caused an average 5-fold greater increase in blood thiamin levels than thiamin mononitrate, with a concomitant greater thiamin concentration in red blood cells. Benfotiamine is converted to S-benzoylthiamin (through removal of the O-monophosphate by the digestive tract), which readily passes through intestinal cells and is converted into thiamin.
Why take Best Benfotiamine?
Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin. Benfotiamine helps maintain healthy cells in the presence of blood glucose, provides support against oxidative stress, and supports healthy aging. Benfotiamine helps maintain healthy glucose metabolism by increasing blood and tissue levels of thiamine pyrophosphate (TPP), the biologically active co-enzyme form of thiamine.TPP acts as a co-enzyme for three critical enzymes involved in glucose metabolism: 1) transketolase, 2) pyruvate dehydrogenase, and 3) a-ketogutarate decarboxylase. The latter two enzymes are involved in utilizing glucose for fuel. Thus, TTP is vital to the cell’s energy supply.
Ecosupplements customer (verified owner) –
Benfotiamine is an active form of B1, which I need due to many health conditions where I don’t convert B vitamins very efficiently. Also the fact that antibiotics completely eliminate our vitamin B1 levels too, I like to have benfotiamine on hand for family members who may have no choice but to go on a course of antibiotics. I like this container size because it means I only order it once or twice a year. The capsules are very small and easy to swallow. I bought the Doctors Best brand because the price was good and this product also has minimal ingredients compared to other brands.
d16tr (verified owner) –
… then this is one supplement you should take. Great price, good product, recommended.
Ecosupplements customer (verified owner) –
small and easy to take capsule is very important as I take over 20 capsules a day. the quality seems great as it quickly helps calm my heart palpitations and reduces nerve pain. nerve pain presents as numbness and tingling in the palms and legs, and in the stomach regions.
Ecosupplements customer (verified owner) –
I had been stressed for too long and tried meditation, exercise to help me deal with it. But this feeling of anxiety would rise at some point during the day and I would have to bear it for hours. After a week I started taking this supplement, my anxiety and associated stress literally disappeared. It also helps me sleep long and peacefully. It saved me. 🙂
LeeG (verified owner) –
Combined with my daily doses of neurontin has has significantly improved the neurophthy pain in the bottoms of my feet.
katz66 (verified owner) –
Can’t say I saw a differance with this. You have to try it for yourself.
Houndjog (verified owner) –
I take this everyday – it is one of those “must have” supplements!
cherrytomatopie (verified owner) –
I can’t fault the brand for this since I have never taken this supplement before but it completely knocked me out (fatigue and brain fog) for about 24 hours after just one dose. Clearly too strong for me, I might taking 1/2 dose but for now not planning to take again.
Ecosupplements customer (verified owner) –
high quality product. it really works as expected. I will definitely have more soon! Thank you very much for that. it was made of high quality ingredients. Also the packaging and sizes were perfect. overall good quality. I love the smell and the look of it. I can’t wait to buy another!
KevDMcC (verified owner) –
My doctor recommended that I take vitamin B1, so I took the regular form for a year. When that didn’t help I started taking this Benfotiamine which is a more absorbable form. I immediately noticed a difference! I’ve been on this for a year now and will continue to take it.
sludgefalls (verified owner) –
Great value for a great product. Easy to swallow capsules.
Ecosupplements customer (verified owner) –
An excellent source of B1! Benfotiamine is a high quality artificial B1. It’s the only artificial vitamin I supplement with. The other ingredient besides benfotiamine is leucine – an amino acid. Both serve to benefit your body, for different reasons, but both are essential. I added it to my diet once I started detox.
Ecosupplements customer (verified owner) –
Benfotiamine is a synthetic B1. Vitamin B1 is naturally water soluble. Benfotiamine is a fat-soluble vitamin B1. Vitamin B1 is involved in the motor of mitochondria which involves glucose metabolism. The more glucose you have in the machine, the higher the blood sugar level and the more vitamin B1 you will be depleted of. With diabetes, there are four main tissues involved, and B1 can help with all of them: 1. Nerves/Brain – Neuropathy 2. Eyes-Retina 3. Kidney – Nephron 4. Heart Vessels – Microvascular Endothelial Dysfunction Benfotiamine: 3 at 5 times more absorption, Protects against oxidation and AGEs, Lowers A1C All diabetics should take this, I’m not a diabetic but, I just take it for other health benefits. B1 involved in many body functions such as the autonomic nervous system and others.
Eddd (verified owner) –
Best price/potency mix of all the products I’ve tried.
Ecosupplements customer (verified owner) –
high quality product. it really works as expected. I will definitely have more soon! Thank you very much for that. it was made of high quality ingredients. Also the packaging and sizes were perfect. overall good quality. I love the smell and the look of it. I can’t wait to buy another!
Justine (verified owner) –
Very very good. Excellent absorption.
Ecosupplements customer (verified owner) –
high quality product. it really works as expected. I will definitely have more soon! Thank you very much for that. it was made of high quality ingredients. Also the packaging and sizes were perfect. overall good quality. I love the smell and the look of it. I can’t wait to buy another!
Ecosupplements customer (verified owner) –
Trusted brand ! Good quality product with good ingredients. high quality product. it really works as expected. I will definitely have more soon! Thank you very much for that. it was made of high quality ingredients. Also the packaging and sizes were perfect. overall good quality. I love the smell and the look of it. I can’t wait to buy another!