Yamamoto Research – Resveratrolo

In the continuously developing “anti-aging” world, it has been defined in many ways, for example as an “elixir of youth”, “universal remedy”, “anti-aging treatment par excellence” and so on, as a panacea that allows you to stay young. Research into its therapeutic potentials is ongoing and needs to be explored, but one thing is certain: it is a natural active ingredient that has several benefits for health promotion. Resveratrol is defined by researchers as a polyphenol in the class of stilbenes, a protector compound produced from red grapes and other plants and fruits, cocoa beans and grapes, (which explains why it is also found in chocolate and in red wine) to defend against parasites. Many studies have shown that resveratrol is an interesting and very powerful antioxidant that protects human health with multiple mechanisms, in particular combating inflammation (bronchitis, hepatitis, etc.) and cardiovascular diseases (arterial hypertension, atherosclerosis, etc.). However, the properties of resveratrol may not only confer cardiovascular benefits to grapes and red wine, but may also be responsible for the therapeutic potential of different fruits, superfoods and medicinal plants. Resveratrol is often presented as a powerful natural antioxidant, since numerous studies have shown that it is able to oppose the accumulation of free radicals, hyperactive elements responsible for various kinds of damage in the body. These antioxidant properties give it an anti-aging action, combating the damage caused by free radicals and allowing it to fight the “premature” aging of the body’s tissues. Moreover, some studies (which will be followed up with more studies on humans) show that it would be able to activate some longevity genes, allowing living beings to increase their life expectancy by 70%, and its effects manifest themselves like those of caloric restriction (the only scientifically proven method of increasing longevity) for the activation of SIR genes.
It is for these reasons that this active ingredient is increasingly widespread in the composition of “anti-aging” and anti-wrinkle cosmetic creams, also because its beneficial action also directly affects the health of the skin because it is able to stimulate the production of collagen, or in the form of food supplements with a high level of health support such as the one we are presenting. But the properties of reservatrol were not limited to antioxidant power, but emerged from studies that limit the secretion of pro-inflammatory substances and consequently attenuate some inflammatory reactions. From a cardiovascular point of view, the researchers were also interested in its potential benefits on the lipid profile, having shown that resveratrol could reduce cholesterol and triglyceride levels, in particular decreasing the rate of bad cholesterol (LDL). The World Health Organisation indicates that resveratrol has a perceptible potential and reduces cardio-vascular risk. Resveratrol is more effective than vitamin E, and works longer against free radical forms, preventing the oxidation of low-density lipoproteins (LDL). It inhibits the aggregation of blood platelets by blocking the action of thrombin and other aggregating factors. It favours the production of nitric oxide which relaxes and dilates the arteries. Reduces the rate of triglycerides and cholesterol in the blood as the intrinsic factor of hypertension endothelin-1.So as an antioxidant, anti-inflammatory, lipid-lowering, hypocholesterolemic, antiplatelet, etc., the benefits of resveratrol for cardiac function are numerous and have been observed in many studies. Also taking into account studies have also shown that intake of resveratrol could increase insulin sensitivity and thus improve the regulation of glucose in patients with type 2 diabetes.
But how is resveratrol so beneficial, like a kind of all-rounder handyman? There have been many studies carried out to date, and its identification in red wine, in the early 90s, aroused great interest and was used to explain the so-called “French paradox”, namely the fact that the inhabitants of southern France, despite a diet high in saturated fats, had a reduced incidence of cardiovascular disease. The habitual consumption of red wine, rich in reveratrol and other flavonoids, was thus indicated as one of the possible protective factors, giving rise to a massive amount of studies on the role that this compound could have in the prevention and treatment of a large number of diseases but the researchers of the University of Florida – The Scripps Research Institute (TSRI), aimed to finally give a clear answer, going on to identify one of the molecular pathways that the precious nutraceutical uses to produce its beneficial action. Dr Kendall Nettles and colleagues found that resveratrol controls the inflammatory response of the body by creating a link to the estrogen receptor, without stimulating estrogenic cell proliferation, opening up new potential pathways for research on certain diseases. In the same study, Nettles, Nwachukwu and colleagues found out when demonstrating its multifactorial approach to the organism, that resveratrol is an effective inhibitor of the pro-inflammatory protein interleukin 6 (IL-6).