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Chasteberry Fruit, also known as Vitex agnus- castus, has a long history of use by women during their periods. If you’re a woman unjustly known as the Wicked Witch of the West several days each month, get set for a little more control in your corner. Studies suggest that it has a progesterone-like effect, which may account for its use in the support of women’s health. Because of this activity, chasteberry has been recommended for a variety of issues common to PMS including mood, body tenderness and water balance.