GABA, gamma-aminobutyric acid, neutralizes these natural stimulants by relaxing the brain. It is most commonly used as an anti-anxiety agent, but has many other reported benefits. Gamma-aminobutyric acid supplementation can help with inflammation issues, meaning it can provide relief for people with PMS or other conditions that accompany chronic pain. When levels drop too low, it’s hard for the body to relax after a stress-induced neurotransmitter release. Low GABA activity leads to anxiety, depression, insomnia and mood disorders. Because of this, its main function in our brain is as a natural brain relaxant that makes us feel good.